All Nations Breath of Life: A Randomized Clinical Trial

Audience: Anyone who currently works with American Indians or conducts randomized clinical trials in smoking cessation could benefit from this poster.

Key Points: Cigarette smoking is the number one cause of preventable death among American Indians and Alaska Natives (AI/ANs), who have the highest smoking rates of all ethnic groups in the US (40.8%), followed by African Americans (24.3%) and Whites (23.6%). In addition, AI/AN smokers have lower quit and abstinent rates compared to other ethnic groups. The lower quit rates could be due to lack of culturally – sensitive quit smoking programs that acknowledge the importance of sacred traditional use of tobacco, while discourage the recreational use of commercial tobacco. This study proposed a 2 - arm group randomized clinical trial to determine the efficacy of culturally – tailored, All Nations of Breath of Life (ANBL) quit smoking program compared to a standard Non-tailored, Current Best Practices (CBP) for American Indians. The study is proposed to be conducted at two sites in the Midwest (Kansas and Oklahoma). Each site (Kansas and Oklahoma) will randomize 28 groups, resulting in 14 groups per arm of the intervention, per site. After baseline telephone assessment, all eligible participants will be group randomized to either ANBL or CBP using permuted blocks based on computer generated random number tables. Participants in both arms will be offered pharmacotherapy at no cost. 

Educational Experience:  Methods used in our randomized trial will be explained in detail.

Benefits: Audience members can learn about methods to conduct randomized trials for smoking cessation.